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4-Hydroxynonenal (HNE)
Method of Measurement (Pre-analytical Tools)
Blood/Plasma
Biomarker Measured
Oxidative stress
Use
Diagnostic
Stage of Development
Clinical trials
Active vs Completed Trials
Completed
Aim/Results
Hydroxynonenal (HNE),a major α,β-unsaturated aldehyde product of n-6 fatty acid oxidation, was higher (P < 0.001) in AD patients compared to controls. HNE was also a good predictor of lipid peroxidation.
Target Population/ Population Being Studied
What is Required from Patients
blood draw, mild discomfort, in-clinic visits
What is Required from the Health System
phlebotomist, equipped lab (e.g., centrifuge), a way to measure the peptide (e.g., mass spectrometer, protein assay kit, ELISA, or western blot)
Sponsor
Department of Biotechnology, PSG College of Technology, Coimbatore, India.