Exert Study
This study evaluates the effects of physical exercise on cognition, functional status, brain atrophy, blood flow, and cerebrospinal fluid biomarkers of Alzheimer's disease in adults with a mild memory impairment. Half of participants will participate in a stretching-balance-range of motion exercise program, while the other half will participate in a moderate- to high-intensity aerobic training program
Qualifying age: Individuals between 65 and 89
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ADNI 3
The Alzheimer's Disease Neuroimaging Initiatiive (ADNI 3) is a landmark partnership and study that for 12 years has profoundly influenced our understanding of Alzheimer's disease by identifying the earliest changes in brain structure and function that signal its onset and progression. The study is led by the National Institute on Aging with support from the FNIH and more than 30 organizations since its launch in 2004. Up to 1,200 new participants are being sought for ADNI3. Clinical, cognitive, imaging, biomarker, and genetic characteristics will be assessed across three groups of participants: cognitively normal, MCI, and mild Alzheimer's dementia. Investigators will evaluate changes in participants' cognition (including memory, reasoning, and language). Participants will undergo clinical, cognitive, and genetic tests, as well as positron emission tomography (PET) and magnetic resonance imaging (MRI) scans and cerebrospinal fluid collection for up to 5 years.
Why is this study important? ADNI 3 builds upon the successes of earlier ADNI phases to identify the earliest signs of AD and will help define the subtle changes that may take place in the brains of older people many years before overt symptoms of the disease appear. The overall goal of the study is to continue to discover, optimize, standardize, and validate clinical trial measures and biomarkers used in AD research.
Qualifying age: Individuals between 55 and 90 who are generally in good health
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ALL of US
We're all human, but we're not all the same. Often our differences like age, ethnicity, lifestyle habits, or where we live can reveal important insights about our health.By participating in All of Us, you may learn more about your health than ever before. If you like, you can share this information with your health care provider.The mission of the All of Us Research Program is simple. We want to speed up health research and medical breakthroughs. To do this, we're asking one million people to lead the way to provide the types of information that can help us create individualized prevention, treatment, and care for all of us.
Why is this study important? The health data we gather from our community of one million people will be added to a database. Researchers can then access this data to further understand how different factors, like environment, lifestyle, and genes, can impact health. This may help develop new medical treatments that are unique to individuals, and enable a future of precision medicine for all of us.We take your privacy very seriously. When you provide personal information, your name and anything that may identify you will be removed, and replaced with a unique code. We'll take care to keep your information secure.
Qualifying age: Enrollment is open to all eligible adults who live in the U.S. People of every race, ethnicity, sex, gender, and sexual orientation are welcome.
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African American Genetic Research Study: It Runs in Our Families
We are seeking two or more family members affected with memory loss or dementia. Study participants are not required to travel and they receive monetary compensation.
Why is this study important? Recruitment for the genetic study is still ongoing. Thanks to your commitment to make a difference, we have over 700 participants enrolled in the study. This participation level led to the discovery of a new gene, ABCA7, found In African Americans.
Qualifying age: Men and women age 60 and older affected by memory loss or families
To learn more, visit the website here, email [email protected] or call Takiyah D. Starks, M.S. at: 888.248.2808