Biomarkers | UsAgainstAlzheimer's

Biomarkers

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Summary of Biomarker Analysis

Method of Measurement
Biomarker Measured
Biomarker Categories

Summary completed October 2019

Biomarkers for Alzheimer’s Disease

Biomarker Tau in the biological fluids (ECTAUSOME)	Biomarker Measured Blood/Plasma, CSF	Method of Measurement Tau	Use Diagnostic, Monitoring	Stage of Development Clinical trials
Biomarker TNF-α (plasma)	Biomarker Measured Blood/Plasma	Method of Measurement Inflammation	Use Diagnostic	Stage of Development Clinical trials
Biomarker 18kDa translocator protein (TSPO)	Biomarker Measured Imaging	Method of Measurement Inflammation	Use Monitoring	Stage of Development Preclinical
Biomarker [18F]T807 PET (TEPTAU)	Biomarker Measured Imaging	Method of Measurement Tau	Use Prognostic	Stage of Development Clinical trials
Biomarker Vascular Cell Adhesion Molecule 1 (VCAM-1)	Biomarker Measured Blood/Plasma	Method of Measurement Neuronal damage	Use Diagnostic, Monitoring, Prognostic	Stage of Development Clinical trials
Biomarker Visinin-Like Protein 1 (Vilip-1, VLP-1)	Biomarker Measured CSF	Method of Measurement Neuronal damage	Use Pharmacodynamic/response	Stage of Development Clinical trials
Biomarker [18F]MK-6240 ([18F]MNI-946)	Biomarker Measured Imaging	Method of Measurement Tau	Use Monitoring, Pharmacodynamic/response, Susceptibility/risk	Stage of Development Clinical trials
Biomarker Vizamyl (Flutemetamol F 18 Injection)	Biomarker Measured Imaging	Method of Measurement Amyloid	Use Diagnostic	Stage of Development In use (FDA approved)
Biomarker [18F]MNI-1126	Biomarker Measured Imaging	Method of Measurement Neuronal damage	Use Monitoring	Stage of Development Clinical trials
Biomarker Matrix metalloproteinase 3 (MMP3)	Biomarker Measured Blood/Plasma, CSF	Method of Measurement Amyloid, Tau	Use Diagnostic, Monitoring	Stage of Development
Biomarker [18F]MNI-958 (APN-0000455; PM-PBB3)	Biomarker Measured Imaging	Method of Measurement Tau	Use Diagnostic, Monitoring	Stage of Development Clinical trials
Biomarker 18F-AV-1451 (F 18 T807)	Biomarker Measured Imaging	Method of Measurement Tau	Use Prognostic, Susceptibility/risk	Stage of Development Clinical trials
Biomarker YKL-40	Biomarker Measured CSF	Method of Measurement Inflammation	Use Diagnostic	Stage of Development Clinical trials

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